METTL14 Rabbit Polyclonal Antibody (QYA10774)
產品名稱：METTL14兔多克隆抗體
貨號：QYA10774
主要參數
應用：WB
適應物種：Human, Mouse, Rat
分子量：60KD
同種型：IgG
儲存溫度：-20℃
建議工作濃度：WB:1:2000-5000
特異性：抗體可以檢測內源性METTL14蛋白
其他名稱：KIAA1627, Methyltransferase like 14
背景
METTL3-METTL14異二聚體可形成N6甲基轉移酶復合物，該復合物能夠介導部分mRNA腺苷殘基的N6位點甲基化，并參與調控生物鐘節律、胚胎干細胞分化及皮質層神經發生過程。
在與METTL3形成的異二聚體中，METTL14主要發揮RNA結合支架功能，負責特異性識別底物而非構成催化核心。
注：本產品僅用于科研用途，不用于診斷和治療。
Product name: METTL14 Rabbit Polyclonal Antibody
Cat: QYA10774
Main parameter
Applications: WB
Reactivity: Human, Mouse, Rat
Protein MW: 60KD
Isotype: IgG
Storage: -20℃
Recommended dilutions: WB:1:2000-5000
Specificity: Antibody can detects endogenous METTL14 protein.
Alternative Names: KIAA1627, Methyltransferase like 14
Background
The METTL3-METTL14 heterodimer forms a N6-methyltransferase complex that methylates adenosine residues at the N6 position of some mRNAs and regulates the circadian clock, differentiation of embryonic stem cells and cortical neurogenesis.
In the heterodimer formed with METTL3, METTL14 constitutes the RNA-binding scaffold that recognizes the substrate rather than the catalytic core.
P.s. This product is only used for scientific research, not for diagnosis and treatment.
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